Western Medicine Diclofenac Sodium Suppositories 100mg B. P. High Quality

• Customization: Available
• State: Solid
• Shape: Powder
• Model NO.: ssilom
• Suitable for: Elderly, Children, Adult
• Pharmaceutical Technology: Chemical Synthesis
• Transport Package: Carton
• Specification: 100mg
• Trademark: OEM
• Origin: China
• HS Code: 300490909
• Production Capacity: 1000000 Boxes/Months

Product Description

Product  Description

Diclofenac Sodium Suppositories, a type of non-steroidal anti-inflammatory drug (NSAID), work by inhibiting cyclooxygenase to reduce prostaglandin synthesis, thus relieving inflammation and pain. Administered rectally, they contain diclofenac sodium as the active ingredient, suitable for easing acute pain in chronic arthritis flare-ups, soft tissue inflammations, post-surgery/trauma discomfort, and primary dysmenorrhea. Adults usually take 50mg 1-2 times daily (up to 100mg daily), while children use 2-3mg/kg daily divided into doses. Common side effects include anal irritation or mild diarrhea, with rare risks like allergic reactions or organ damage from long-term/overuse. Contraindicated in allergic individuals, those with severe liver/kidney issues or ulcers, they offer a gastrointestinal-friendly alternative via rectal delivery, bypassing oral irritation and partially avoiding first-pass metabolism. Always use under medical guidance and store out of children's reach.

 

 

 

Main Ingredients

• Active ingredient: Diclofenac Sodium. Excipients typically include polyethylene glycol, stearic acid, etc. (excipients may vary across formulations).

Mechanism of Action

• Inhibits the activity of cyclooxygenase (COX-1 and COX-2), reducing prostaglandin synthesis to alleviate inflammatory responses and pain perception.

Indications

• Relieves acute pain during flare-ups of chronic arthritis (e.g., rheumatoid arthritis, osteoarthritis);
• Treats non-articular rheumatic inflammations of soft tissues (e.g., tenosynovitis, bursitis);
• Alleviates acute pain from postoperative conditions, trauma, overexertion, primary dysmenorrhea, etc.

Dosage (Follow medical advice)

• Adults: 50mg per dose, 1-2 times daily via rectal administration (insert into the anus). The daily dose may increase to 100mg (divided into 1-2 doses) as needed.
• Children: 2-3mg/kg daily based on body weight, administered in 1-2 divided doses (specific adjustments required according to age and condition).

Adverse Reactions

• Common: Possible anal irritation, rectal discomfort, or mild diarrhea;
• Rare: Occasional allergic reactions (e.g., rash, itching), gastrointestinal bleeding, liver/kidney function impairment (risk increases with long-term or excessive use).

Precautions

• Contraindications: Contraindicated in patients allergic to diclofenac sodium or other NSAIDs, those with severe hepatic/renal insufficiency, or peptic ulcer disease; use with caution in pregnant and lactating women.
• Medication warnings:
  • Avoid concurrent use with other NSAIDs to prevent increased risks of gastrointestinal and hepatorenal damage;
  • Refrain from alcohol during treatment to reduce gastric mucosal injury;
  • Store suppositories in a sealed container out of children's reach.

Dosage Form Advantages

• Rectal administration avoids direct gastrointestinal irritation from oral use, suitable for patients with gastrointestinal sensitivity or swallowing difficulties;
• Drugs are absorbed through rectal mucosa, partially bypassing hepatic first-pass metabolism, potentially enabling faster onset (varies by individual).

 

Adults and Elderly:

Relief of all grades of pain and inflammation in a wide range of conditions, including:

(i)	arthritic conditions: rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout,
(ii)	acute musculo-skeletal disorders such as periarthritis (for example frozen shoulder), tendinitis, tenosynovitis, bursitis,
(iii)	other painful conditions resulting from trauma, including fracture, low back pain, sprains, strains, dislocations, orthopaedic, dental and other minor surgery.

 

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RFQ
Q: Are you a manufacturer?
A: Yes, we have established our own factory since 2002, with the latest GMP certification, independent R&D center, and advanced production equipment. The group has been listed as a reputable brand by CCTV. We can strictly control product quality to ensure you can buy high-quality, cost-effective products.

Q: What products can you provide?
A: We have multiple production lines for powders, injections, premixes, oral liquids, and biological additives, we are leaders in the production of veterinary drugs, animal feed, feed additives, pharmaceutical intermediates, pharmaceutical raw materials. Our diverse range of products includes offerings for pets, poultry, cattle, sheep, pigs, and aquatic species.

Q: Do you test all your goods before delivery?
A: Yes, we conduct 100% testing before delivery to ensure that each batch of veterinary drugs undergoes strict quality testing, and if you require, we warmly welcome third-party testing with international authorization for our products.

Q: Can we have the sample?
A: Of course, you can place a sample order first to test the company's quality and service. For some products, we can provide free samples.

Q: What is the MOQ (minimum order quantity)?
A: We have a significant advantage in MOQ because we offer small MOQ. 100 bottles of injection and 1kg of powder.

Q: Can I use my own design package?
A: Yes, OEM service is available. We can customize packaging and labels to create a unique brand for dealers. In addition, we can also customize specifications and formulas according to different requirements.

Q: How about delivery time?
A: We have ample inventory and are ready to ship. Most of our factory orders are normally shipped within 3-5 days upon receiving your payment.

Q: Do you provide after sales service?
A: We have a clear division of work and offer after-sales service within 8 hours. If there are any quality problems, we will be responsible to the end.