Customization: | Available |
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Shape: | Liquid |
Shelf Life: | 2 Years |
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Indications
Ascorbic acid is recommended for the prevention and treatment of scurvy. Its parenteral administration is desirable for patients with an acute deficiency or for those whose absorption of orally ingested ascorbic acid is uncertain.
Symptoms of mild deficiency may include faulty bone and tooth development, gingivitis, bleeding gums, and loosened teeth. Febril states, chronic illness, and infection (pneumonia, whooping cough, tuberculosis, diphtheria, sinusitis, rheumatic fever, etc.) increases the need for ascorbic acid.
Contra-indications
There are no contraindications to the administration of ascorbic acid.
Adverse effects
Transient mild soreness may occur at the site of intramuscular or subcutaneous injection. Too-rapid intravenous administration of the solution may cause temporary faintness or dizziness.
Drug Interactions
Limited evidence suggests that ascorbic acid may influence the intensity and duration of action of bishydroxycoumarin.
Treatment/antidote in the event of overdose
Vitamin C overdose can cause an increased risk of developing kidney stones because it increases the absorption of iron. Vitamin C overdose should always be avoided and must be avoided especially by people with iron overload diseases such as Hemochromatosis. Such patients should avoid intake of Vitamin C because it increases the accumulation of non-heme iron.
Storage instructions
Keep it under seal in cool and dry place. Protect from light.
Validity
Two Years
Storage | Shading, airtight (10~30 ºC) storage. |
Notice | Vitamin C requirements are increased in the following conditions: (1) Patients undergoing chronic hemodialysis, gastrointestinal diseases (chronic diarrhea, after gastric or ilectomies), tuberculosis, cancer, ulcer disease, hyperthyroidism, fever, infection, trauma, burns, surgery, etc. (2) Patients receiving parenteral nutrition due to strict diet control or choice, weight drop due to malnutrition, and during pregnancy and lactation. (3) the application of barbiturates, tetracycline, salicylic acid, or vitamin C as urinary system acidification drugs. |
1. Vitamin C has yet to be confirmed: the function of the following situations to prevent or treat cancer, gingivitis, fester, bleeding, blood in urine, retinal hemorrhage, depression, dental caries, anemia, aging, acne and infertility, hardening of the arteries, ulcer disease, tuberculosis, dysentery, collagen disease, fracture, skin ulcer, hay fever, drug poisoning, vascular embolization, colds, etc. 2. Interference with diagnosis. Large doses will affect the results of the following diagnostic tests: (1) Fecal occult blood can cause false positive. (2) it can interfere with the automatic analysis results of serum lactate dehydrogenase and serum amino transferase concentration. (3) False positives can be caused by urine sugar (copper sulfate method) and glucose (oxidase method). (4) Increased concentrations of oxalate, urate and cysteine in urine. (5) serum bilirubin concentration decreased. (6) Decreased urine pH. 3. Caution should be exercised in the following cases: (1) cysteinuria. (2) the gout. (3) hyperoxalate uria. (4) Oxalate deposition. (5) urate kidney stones. (6) diabetes (because vitamin C may interfere with blood glucose measurement). (7) Glucose-6-phosphate dehydrogenase deficiency. (8) hemochromatism. (9) Siderocytic anemia or thalassemia. (10) Sickle cell anemia. 4. Long-term large doses of sudden drug withdrawal, it is possible to appear scurvy symptoms, so it is advisable to gradually reduce the drug withdrawal. [Medication for pregnant and lactating Women] This product can be secreted into milk through the placenta. When pregnant women take large doses, can also produce infant scurvy. 5. Medication for children Recommended dietary intakes (RDA, 1980) : 45mg for children aged 4-6 years and 60mg for adults aged 7 years and older. |
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[Drug interaction] (1) High dose of vitamin C can interfere with the anticoagulant effect of anticoagulants. (2) With barbiturate or pulmidone, etc., can promote the excretion of vitamin C increased. (3) Sodium cellulose phosphate can promote the metabolism of vitamin C into oxalate. (4) Long-term or massive application of vitamin C can interfere with the effect of disulfide on ethanol. (5) Salicylic acids increase the excretion of vitamin C. (6) Should not be compatible with alkaline drugs (such as aminophylline, sodium bicarbonate, sodium glutamate, etc.), riboflavin, trichlorot-butyl alcohol, copper, iron (trace) solution, so as not to affect the curative effect. (7) with vitamin K3, because the latter has oxidation, can produce REDOX reaction, so that the curative effect of both weakened or disappeared. (8) Contraindicated with aminophylline, bleomycin, cefazolin, cefpielin, conjugative estrogen, dextran, doxalum, erythromycin, methoxymycin, penicillin G, vitamin K, warfarin, sodium bicarbonate. 4. Drug overdose. 1 ~ 4g a day, can cause diarrhea, rash, increased gastric acid, gastric reflux, urinary calculus, urinary oxalate and urate discharge increased, deep venous thrombosis, hemolysis or coagulation, sometimes can lead to reduced phagocytosis of white blood cells. When the daily dosage exceeds 5g, it can lead to hemolysis and fatal in severe cases. When applied in large quantities in pregnant women, infant scurvy may occur. When necessary, adults 2 ~ 4g each time, 1 ~ 2 times a day, or according to the doctor's advice. |