Doxycycline Capsules are a versatile broad-spectrum antibiotic with excellent activity against atypical pathogens and tick-borne diseases. They offer advantages over other tetracyclines, including better gastrointestinal tolerance, reduced need for dose adjustment in renal failure, and once-daily dosing for many indications. While widely used for infections like Lyme disease, acne, and STIs, caution is essential in pregnant individuals, young children, and those at risk of photosensitivity or intracranial hypertension. Always confirm pathogen susceptibility and weigh risks, particularly in vulnerable populations.
Trade Names: Common trade names include Vibramycin, Doryx, Monodox (varies by region).
Dosage Form: Hard gelatin capsules containing doxycycline hyclate or monohydrate (usually white to yellowish powder).
Specifications: Common strengths: 50 mg, 100 mg, 200 mg (expressed as doxycycline base).
Pharmacology
Mechanism of Action:
Binds to the 30S ribosomal subunit of bacteria, inhibiting protein synthesis and exerting bacteriostatic effects. Similar to other tetracyclines but with enhanced lipid solubility and longer half-life.
Spectrum of Activity:
Gram-positive bacteria: Streptococci, Staphylococci (including some tetracycline-sensitive MRSA strains in vitro), Clostridium.
Gram-negative bacteria: Haemophilus, Neisseria, Escherichia coli (variable sensitivity due to resistance), Klebsiella.
Sexually Transmitted Infections (STIs): Chlamydia, gonorrhea (as adjunct to cephalosporins), syphilis (alternative to penicillin).
Gastrointestinal Infections: Brucellosis (in combination), cholera, traveler's diarrhea (prophylaxis in high-risk areas).
Other Infections: Q fever (Coxiella burnetii), tularemia, leptospirosis.
Non-Infectious Uses:
Rosacea: Low-dose therapy (40 mg daily) for inflammatory lesions.
Malaria Prophylaxis: For chloroquine-resistant regions (e.g., sub-Saharan Africa).
Rheumatoid Arthritis: Adjunctive therapy for anti-inflammatory effects (off-label use).
Company Introduce
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RFQ Q: Are you a manufacturer? A: Yes, we have established our own factory since 2002, with the latest GMP certification, independent R&D center, and advanced production equipment. The group has been listed as a reputable brand by CCTV. We can strictly control product quality to ensure you can buy high-quality, cost-effective products.
Q: What products can you provide? A: We have multiple production lines for powders, injections, premixes, oral liquids, and biological additives, we are leaders in the production of veterinary drugs, animal feed, feed additives, pharmaceutical intermediates, pharmaceutical raw materials. Our diverse range of products includes offerings for pets, poultry, cattle, sheep, pigs, and aquatic species.
Q: Do you test all your goods before delivery? A: Yes, we conduct 100% testing before delivery to ensure that each batch of veterinary drugs undergoes strict quality testing, and if you require, we warmly welcome third-party testing with international authorization for our products.
Q: Can we have the sample? A: Of course, you can place a sample order first to test the company's quality and service. For some products, we can provide free samples.
Q: What is the MOQ (minimum order quantity)? A: We have a significant advantage in MOQ because we offer small MOQ. 100 bottles of injection and 1kg of powder.
Q: Can I use my own design package? A: Yes, OEM service is available. We can customize packaging and labels to create a unique brand for dealers. In addition, we can also customize specifications and formulas according to different requirements.
Q: How about delivery time? A: We have ample inventory and are ready to ship. Most of our factory orders are normally shipped within 3-5 days upon receiving your payment.
Q: Do you provide after sales service? A: We have a clear division of work and offer after-sales service within 8 hours. If there are any quality problems, we will be responsible to the end.