Product Description
Oxytetracycline hydrochloride for veterinary use is a key tool in treating bacterial infections in animals, but its use requires strict veterinary guidance to minimize resistance and residue risks. While largely replaced by safer alternatives in human medicine, it remains relevant in veterinary contexts for economic animals. Prioritize rational dosing, withdrawal periods, and compliance with food safety standards to balance efficacy and public health.
| Product name |
Oxytetracycline Hydrochloride |
| Composition |
Oxytetracycline\ |
| Dosage and Administration |
Calculated with this product,Oral administration: one dose, 0.2~0.3g for each 1kg body weight of chicken, twice a day, for successive 5 days; Mixed drinking: 0.6g for every 1L of water for 3 to 5 days. |
| Storage |
Keep out of light and sealed. |
Basic Information
- Class: A broad-spectrum tetracycline antibiotic that inhibits bacterial protein synthesis, exclusively for animal use and (strictly prohibited for human consumption).
- Formulations: Commonly available as injections, tablets, premixes, and soluble powders for livestock, poultry, and aquaculture.
Pharmacology and Antimicrobial Spectrum
- Mechanism: Binds to the 30S subunit of bacterial ribosomes, blocking aminoacyl-tRNA binding and inhibiting peptide chain elongation.
- Activity: Effective against Gram-positive/negative bacteria (e.g., E. coli, Salmonella, Pasteurella), mycoplasma, chlamydia, and spirochetes, though resistance is widespread.
Veterinary Indications
- Livestock & Poultry:
- Swine: Mycoplasmal pneumonia, infectious pleuropneumonia, neonatal diarrhea.
- Poultry: Colibacillosis, pullorum disease, chronic respiratory disease (mycoplasma).
- Cattle/Sheep: Pasteurellosis, brucellosis, mastitis.
- Aquaculture: Treats bacterial gill rot, enteritis in fish, and vibriosis in shrimp/crab.
- Prophylaxis: Reduces stress-related infections during transportation or as a growth promoter (subject to residue standards).
Usage and Dosage
(Adjust based on species, weight, and infection; examples below):
- Oral:
- Swine/Cattle: 10-20 mg/kg body weight, twice daily, for 3-5 days.
- Poultry: Mixed in water/feed at 50-100 mg/L/kg, for 3-5 days.
- Injection:
- IM/IV: 5-10 mg/kg, once or twice daily; severe cases follow veterinary advice.
- Premixes: Added to feed for prophylaxis/growth promotion (observe withdrawal periods).
Key Considerations
-
Resistance Management:
- Avoid prolonged use; rotate with other antibiotics to reduce resistance.
- Aquaculture: Follow withdrawal periods (e.g., ≥21 days for fish) to prevent residue (exceeding limits).
-
Drug Interactions:
- Avoid antacids, calcium/iron supplements (reduce absorption).
- Do not combine with penicillins/cephalosporins (may antagonize bactericidal effects).
-
Animal Safety:
- Young Animals: Potential dental discoloration (e.g., piglets), but risks are weighed against treatment needs.
- Liver/Kidney Impairment: Use with caution to avoid metabolic stress.
-
Operator Safety:
- Wear gloves/masks; avoid skin contact or inhalation (may cause irritation/allergy).
- Dispose of waste drugs/packaging as veterinary hazardous waste.
Adverse Effects
- GI Upset: Vomiting/diarrhea in monogastric animals.
- Superinfection: Risk of fungal or resistant bacterial overgrowth with prolonged use.
- Local Reactions: Pain, inflammation, or necrosis at injection sites (use deep IM, avoid IV extravasation).
- Residue Risks: Unapproved use may lead to drug residues in meat, eggs, or milk, violating food safety standards.
Contraindications and Cautions
- Contraindicated:
- Animals allergic to tetracyclines.
- Laying hens (drug excreted in eggs, affecting quality).
- Cautious Use:
- Late-pregnancy livestock (potential fetal bone development impact).
- Severely renal-impaired animals.
Company Introduce
Related Products
RFQ
Q: Are you a manufacturer?
A: Yes, we have established our own factory since 2002, with the latest GMP certification, independent R&D center, and advanced production equipment. The group has been listed as a reputable brand by CCTV. We can strictly control product quality to ensure you can buy high-quality, cost-effective products.
Q: What products can you provide?
A: We have multiple production lines for powders, injections, premixes, oral liquids, and biological additives, we are leaders in the production of veterinary drugs, animal feed, feed additives, pharmaceutical intermediates, pharmaceutical raw materials. Our diverse range of products includes offerings for pets, poultry, cattle, sheep, pigs, and aquatic species.
Q: Do you test all your goods before delivery?
A: Yes, we conduct 100% testing before delivery to ensure that each batch of veterinary drugs undergoes strict quality testing, and if you require, we warmly welcome third-party testing with international authorization for our products.
Q: Can we have the sample?
A: Of course, you can place a sample order first to test the company's quality and service. For some products, we can provide free samples.
Q: What is the MOQ (minimum order quantity)?
A: We have a significant advantage in MOQ because we offer small MOQ. 100 bottles of injection and 1kg of powder.
Q: Can I use my own design package?
A: Yes, OEM service is available. We can customize packaging and labels to create a unique brand for dealers. In addition, we can also customize specifications and formulas according to different requirements.
Q: How about delivery time?
A: We have ample inventory and are ready to ship. Most of our factory orders are normally shipped within 3-5 days upon receiving your payment.
Q: Do you provide after sales service?
A: We have a clear division of work and offer after-sales service within 8 hours. If there are any quality problems, we will be responsible to the end.
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