Injectable amoxicillin sodium is a commonly used semi-synthetic penicillin antibiotic. It works by inhibiting bacterial cell wall synthesis, effective against many gram-positive and gram-negative bacteria. Indications include respiratory, urinary, digestive, skin infections, as well as otitis media and septicemia. Dosage varies by age, weight, and condition: adults 0.5-1g every 6-8h (max 6g/day), children 20-40mg/kg/day (40-80mg/kg for severe cases). Common side effects: allergic reactions (rash, anaphylaxis), GI issues (nausea, diarrhea). Contraindicated in penicillin-allergic patients. Precautions: ask about allergy history, perform skin test if needed, adjust dose for renal impairment, monitor for superinfection. Store in a cool, dry place away from light. Use under medical guidance, do not use or discontinue arbitrarily.
Basic Information
Main Ingredient: Amoxicillin sodium.
Class: Beta-lactam antibiotics, penicillin class.
Pharmaceutical Form: Injection, which is usually a white to off-white powder or crystal.
Pharmacological Action
Mechanism of Action: It works by inhibiting the synthesis of the bacterial cell wall, leading to the death of bacteria, thus playing an antibacterial role.
Antibacterial Spectrum: It has a good antibacterial effect on many gram-positive bacteria and gram-negative bacteria, such as Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus (non-methicillin-resistant strain), Escherichia coli, Haemophilus influenzae, etc.
Indications
It is suitable for the treatment of the following infections caused by sensitive bacteria:
Respiratory system infections: Such as acute bronchitis, chronic bronchitis acute attack, pneumonia, etc.
Urinary and reproductive system infections: Such as urethritis, cystitis, pyelonephritis, cervicitis, etc.
Digestive system infections: Such as cholangitis, cholecystitis, etc.
Skin and soft tissue infections: Such as folliculitis, furuncle, carbuncle, cellulitis, wound infection, etc.
Other infections: Such as otitis media, sinusitis, septicemia, etc.
Usage and Dosage
The specific dosage depends on the patient's age, weight, condition, and the severity of the infection. It is usually administered by intravenous infusion or intramuscular injection.
Adults: The usual dose is 0.5 to 1 g each time, administered every 6 to 8 hours. For severe infections, the dose can be increased appropriately, but the daily maximum dose generally does not exceed 6 g.
Children: The dosage is calculated according to body weight, usually 20 to 40 mg/kg per day, divided into 2 to 3 administrations. For severe infections, the dose can be increased to 40 to 80 mg/kg per day.
Renal Impairment Patients: The dosage needs to be adjusted according to the degree of renal function impairment.
Adverse Reactions
Allergic Reactions: This is the more common adverse reaction, which can manifest as rash, itching, urticaria, angioedema, anaphylactic shock, etc. Anaphylactic shock is a serious allergic reaction and can be life-threatening, so it is necessary to ask the patient about the allergy history before use, and conduct a skin test if necessary.
Gastrointestinal Reactions: Such as nausea, vomiting, diarrhea, abdominal discomfort, etc. These reactions are usually mild and can be relieved after stopping the drug.
Hematological Disorders: Rarely, it may cause anemia, leukopenia, thrombocytopenia, etc.
Liver and Kidney Function Abnormalities: Rarely, it may cause transient elevation of liver enzymes or slight changes in renal function.
Other: Such as dizziness, headache, superinfection (such as oral candidiasis, vaginal candidiasis, etc.), etc.
Contraindications and Precautions
Contraindications:
Patients with a history of allergy to penicillin drugs are prohibited.
Patients with a history of allergic shock to penicillin are prohibited.
Precautions:
Allergy Warning: Before using this drug, it is necessary to carefully ask the patient about the history of drug allergy, especially the allergy history to penicillins, cephalosporins, and other beta-lactam antibiotics. For patients with a history of penicillin allergy or allergic diathesis, it should be used with caution. Skin test for penicillin should be performed before use as required. Once allergic reactions occur, the drug should be stopped immediately and appropriate treatment measures should be taken.
Renal Function Monitoring: For patients with severe renal impairment, the dosage should be adjusted under the guidance of a doctor, and renal function should be monitored during the treatment.
Gastrointestinal Reaction: If severe gastrointestinal reactions such as persistent diarrhea occur during the use of the drug, it may be a sign of pseudomembranous colitis, and the drug should be stopped and corresponding treatment should be taken in time.
Superinfection: Long-term use of this drug may lead to the overgrowth of non-sensitive bacteria, causing superinfection. If symptoms such as oral ulcers, vaginal itching, and abnormal leucorrhea occur, it should be dealt with in time.
Pregnancy and Lactation: This drug can pass through the placenta and enter breast milk. Pregnant women and lactating women should use it with caution only when the benefits outweigh the risks.
Drug Interactions: It may interact with other drugs, such as probenecid, which can reduce the excretion of amoxicillin and increase its blood concentration; allopurinol may increase the incidence of rash. If other drugs are being used, it is necessary to inform the doctor in advance to avoid adverse drug interactions.
Storage Conditions: It should be stored in a cool, dry place, away from light, and sealed.
Drug Storage
Store in a cool and dry place, away from light, and keep sealed. The specific storage conditions should also refer to the product instructions.
Generic name
Amoxicillin sodium For Injection
Strength
500mg
Standard
BP
Shelf life
3 Years
Company Introduce
Related Products
RFQ Q: Are you a manufacturer? A: Yes, we have established our own factory since 2002, with the latest GMP certification, independent R&D center, and advanced production equipment. The group has been listed as a reputable brand by CCTV. We can strictly control product quality to ensure you can buy high-quality, cost-effective products.
Q: What products can you provide? A: We have multiple production lines for powders, injections, premixes, oral liquids, and biological additives, we are leaders in the production of veterinary drugs, animal feed, feed additives, pharmaceutical intermediates, pharmaceutical raw materials. Our diverse range of products includes offerings for pets, poultry, cattle, sheep, pigs, and aquatic species.
Q: Do you test all your goods before delivery? A: Yes, we conduct 100% testing before delivery to ensure that each batch of veterinary drugs undergoes strict quality testing, and if you require, we warmly welcome third-party testing with international authorization for our products.
Q: Can we have the sample? A: Of course, you can place a sample order first to test the company's quality and service. For some products, we can provide free samples.
Q: What is the MOQ (minimum order quantity)? A: We have a significant advantage in MOQ because we offer small MOQ. 100 bottles of injection and 1kg of powder.
Q: Can I use my own design package? A: Yes, OEM service is available. We can customize packaging and labels to create a unique brand for dealers. In addition, we can also customize specifications and formulas according to different requirements.
Q: How about delivery time? A: We have ample inventory and are ready to ship. Most of our factory orders are normally shipped within 3-5 days upon receiving your payment.
Q: Do you provide after sales service? A: We have a clear division of work and offer after-sales service within 8 hours. If there are any quality problems, we will be responsible to the end.
Audited Supplier 
){kind=link}