Collagenase Injection is an injectable preparation with collagenase as the main ingredient, which works by specifically breaking down abnormal or excessive collagen in target tissues through local injection. It is mainly used to treat Dupuytren's contracture, alleviate Peyronie's disease, and assist in managing tissue adhesions or scars. Administered by professional medical personnel, it may cause transient local reactions like pain or swelling, and requires attention to allergy risks and strict adherence to indications. As a targeted biological agent, it offers a non-surgical or adjuvant treatment option for specific diseases, with its application relying on accurate diagnosis and professional operation to ensure efficacy and safety.
Collagenase Injection
Collagenase Injection is an injectable preparation containing collagenase as the main ingredient. Leveraging collagenase's ability to specifically break down collagen, it plays a significant role in the medical field. Below is a detailed explanation covering its core mechanism, main indications, administration methods, and precautions:
Core Mechanism of Action
The key function of Collagenase Injection is to deliver collagenase directly to target tissues via injection, where it specifically hydrolyzes excessively accumulated or abnormal collagen. Collagen is a key component of connective tissue; if it accumulates excessively in local areas (such as scar tissue or adhesions), it may impair tissue function. Collagenase breaks down its structure into absorbable small molecules, thereby improving tissue elasticity, relieving compression, or reducing adhesions.
Main Clinical Indications
Treating Dupuytren's Contracture
This is one of the most common applications of collagenase injection. The condition arises from excessive collagen proliferation and contraction in the palmar fascia, causing fingers (especially the ring and little fingers) to lose normal extension. Injecting collagenase into the contracted fascial tissue decomposes abnormal collagen, relieving contracture and restoring finger mobility.
Alleviating Peyronie's Disease
This disease is characterized by abnormal collagen deposition in the tunica albuginea of the penile corpus cavernosum, forming plaques that lead to penile curvature, pain, or erectile dysfunction. Collagenase Injection can be administered directly into the plaques to degrade excess collagen, reducing plaque size and alleviating symptoms.
Assisting in Managing Tissue Adhesions or Scars
After certain surgeries or injuries, local tissues may form abnormal adhesions or scars (e.g., tendon adhesions). Under medical guidance, Collagenase Injection can be used locally to help break down collagen and improve tissue mobility.
Administration and Precautions
Administration: It is administered via local injection, strictly by professional medical personnel. The injection site, dosage, and course of treatment are determined based on specific conditions (e.g., Dupuytren's contracture may require multiple injections).
Precautions:
Allergy risk: Contraindicated in individuals allergic to collagenase or other components in the preparation; allergy history must be confirmed before use.
Local reactions: Transient pain, swelling, or erythema may occur after injection, usually resolving on their own. Severe inflammation or infection requires prompt medical attention.
Strict indication adherence: It should only be used after a clear diagnosis to avoid misuse (e.g., injection into normal tissues may cause unnecessary collagen breakdown).
Product Description
Product Name:
Collagenase
CAS:
9001-12-1
Company Introduce
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RFQ Q: Are you a manufacturer? A: Yes, we have established our own factory since 2002, with the latest GMP certification, independent R&D center, and advanced production equipment. The group has been listed as a reputable brand by CCTV. We can strictly control product quality to ensure you can buy high-quality, cost-effective products.
Q: What products can you provide? A: We have multiple production lines for powders, injections, premixes, oral liquids, and biological additives, we are leaders in the production of veterinary drugs, animal feed, feed additives, pharmaceutical intermediates, pharmaceutical raw materials. Our diverse range of products includes offerings for pets, poultry, cattle, sheep, pigs, and aquatic species.
Q: Do you test all your goods before delivery? A: Yes, we conduct 100% testing before delivery to ensure that each batch of veterinary drugs undergoes strict quality testing, and if you require, we warmly welcome third-party testing with international authorization for our products.
Q: Can we have the sample? A: Of course, you can place a sample order first to test the company's quality and service. For some products, we can provide free samples.
Q: What is the MOQ (minimum order quantity)? A: We have a significant advantage in MOQ because we offer small MOQ. 100 bottles of injection and 1kg of powder.
Q: Can I use my own design package? A: Yes, OEM service is available. We can customize packaging and labels to create a unique brand for dealers. In addition, we can also customize specifications and formulas according to different requirements.
Q: How about delivery time? A: We have ample inventory and are ready to ship. Most of our factory orders are normally shipped within 3-5 days upon receiving your payment.
Q: Do you provide after sales service? A: We have a clear division of work and offer after-sales service within 8 hours. If there are any quality problems, we will be responsible to the end.
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