Procaine penicillin & dihydrostreptomycin veterinary injectable suspension combats bacterial infections in livestock/poultry (e.g., pneumonia, mastitis). Given IM/SC (20k-40k U/kg penicillin for livestock), it requires dissolution, warns of local irritation/ototoxicity, and needs veterinary prescription with withdrawal period compliance.
Procaine Penicillin & Dihydrostreptomycin Injectable Suspension for Veterinary
I. Basic Drug Information
Composition:
Procaine Penicillin: A long-acting penicillin that inhibits bacterial cell wall synthesis.
Dihydrostreptomycin: An aminoglycoside antibiotic that suppresses bacterial protein synthesis.
Dosage Form: Injectable suspension, to be dissolved before intramuscular or subcutaneous injection.
II. Pharmacological Action
Procaine penicillin is effective against Gram-positive bacteria (e.g., Streptococcus, Staphylococcus) with prolonged action.
Dihydrostreptomycin targets Gram-negative bacteria (e.g., E. coli, Salmonella) and some Gram-positive bacteria.
The combination expands the antibacterial spectrum, suitable for mixed infections in animals.
III. Indications (Veterinary Use)
Treats bacterial infections sensitive to penicillin and dihydrostreptomycin in livestock and poultry, including:
Livestock: Pneumonia, mastitis, endometritis, septicemia in cattle, sheep, and pigs.
Poultry: Colibacillosis, salmonellosis, chronic respiratory disease in chickens and ducks.
Other conditions: Wound infections, cellulitis, brucellosis (under veterinary guidance).
IV. Dosage and Administration (Veterinary Example, Follow Veterinary Advice)
Intramuscular/Subcutaneous Injection:
Livestock: 20,000-40,000 units/kg (based on penicillin) once, 1-2 times daily, for 3-5 days.
Poultry: 10,000-20,000 units/kg (based on penicillin) once daily, for 2-3 days.
Note: Dissolve with sterile water for injection, shake well before use; avoid intravenous administration.
V. Adverse Reactions and Contraindications
Adverse Reactions:
Local irritation (swelling, pain at the injection site).
Rare allergic reactions (rash, dyspnea).
Potential ototoxicity (hearing loss) and nephrotoxicity (more sensitive in young animals) from dihydrostreptomycin.
Contraindications:
Animals allergic to penicillins or aminoglycosides.
Young animals (e.g., piglets, chicks) due to high ototoxicity risk.
VI. Precautions
Before Use:
Confirm the infection type and avoid abuse.
Adjust dosage for animals with renal insufficiency.
During Use:
Observe the injection site and avoid repeated injections at the same location.
Monitor appetite, urine output, and hearing (discontinue if abnormalities occur).
Withdrawal Period:
Adhere to withdrawal periods for food-producing animals (e.g., 28 days for pigs and cattle, subject to the label).
Compatibility:
Avoid concurrent use with potent diuretics (may exacerbate ototoxicity).
Do not mix with acidic or alkaline drugs for injection.
VII. Storage
Store in a cool, dry place protected from light at ≤25°C (77°F).
Use the dissolved suspension promptly to prevent deterioration.
VIII. Veterinary Medication Principles
Require a veterinary prescription; administer strictly according to dosage and course to prevent drug resistance.
Prioritize drug sensitivity testing and narrow-spectrum antibiotics over(compound preparations) when possible.
Dispose of waste solution properly to avoid environmental pollution.
Company Introduce
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RFQ Q: Are you a manufacturer? A: Yes, we have established our own factory since 2002, with the latest GMP certification, independent R&D center, and advanced production equipment. The group has been listed as a reputable brand by CCTV. We can strictly control product quality to ensure you can buy high-quality, cost-effective products.
Q: What products can you provide? A: We have multiple production lines for powders, injections, premixes, oral liquids, and biological additives, we are leaders in the production of veterinary drugs, animal feed, feed additives, pharmaceutical intermediates, pharmaceutical raw materials. Our diverse range of products includes offerings for pets, poultry, cattle, sheep, pigs, and aquatic species.
Q: Do you test all your goods before delivery? A: Yes, we conduct 100% testing before delivery to ensure that each batch of veterinary drugs undergoes strict quality testing, and if you require, we warmly welcome third-party testing with international authorization for our products.
Q: Can we have the sample? A: Of course, you can place a sample order first to test the company's quality and service. For some products, we can provide free samples.
Q: What is the MOQ (minimum order quantity)? A: We have a significant advantage in MOQ because we offer small MOQ. 100 bottles of injection and 1kg of powder.
Q: Can I use my own design package? A: Yes, OEM service is available. We can customize packaging and labels to create a unique brand for dealers. In addition, we can also customize specifications and formulas according to different requirements.
Q: How about delivery time? A: We have ample inventory and are ready to ship. Most of our factory orders are normally shipped within 3-5 days upon receiving your payment.
Q: Do you provide after sales service? A: We have a clear division of work and offer after-sales service within 8 hours. If there are any quality problems, we will be responsible to the end.