Good Quality Analgin Injection Metamizole Sodique 500mg Im/IV 10 Ampoules Glass with GMP

• Customization: Available
• Shelf Life: 2 Years
• Suitable for: Adult Children
• Model NO.: ssilom
• Delivery Time: 30~60 Days
• OEM/ODM: Support
• Transport Package: Carton
• Specification: 5ml
• Trademark: OEM
• Origin: China
• Production Capacity: 1000000 Boxes/Months

Product Description

Product  Description

 

Analgin Injection, containing Metamizole Sodium, is a pyrazolone-class drug for emergency fever reduction and acute pain relief via intramuscular injection. However, due to serious risks like agranulocytosis and organ damage, its use has declined. Adult dose: 0.25-0.5g (≤1.8g/day); pediatric dose: 5-10mg/kg. Contraindicated in allergic individuals, pregnant women, and newborns. Safer alternatives like paracetamol are now preferred.

 

 

 

 

 

 

 

Basic Information

• Generic Name: Analgin Injection
• Main Component: Metamizole Sodium, a pyrazolone-class antipyretic and analgesic that works by inhibiting prostaglandin synthesis.

Pharmacological Actions

• Antipyretic Effect: Significantly reduces body temperature in febrile patients (no effect on normal body temperature), with rapid and sustained action.
• Analgesic Effect: Relieves mild to moderate pain (e.g., headache, toothache, muscle pain, joint pain) but is ineffective for visceral colic.
• Anti-Inflammatory Effect: Weak; clinically used primarily for symptomatic treatment rather than anti-inflammation.

Indications

• Emergency (fever reduction) in acute high fever when other measures fail (short-term use only).
• Relief of acute pain (e.g., severe headache, toothache, postoperative pain), though clinical use has declined due to side effect risks.

Usage and Dosage

• Administration Route: Intramuscular injection (intravenous injection is prohibited due to severe adverse reaction risks).
• Adult Dose: 0.25-0.5 g per injection, with a maximum daily dose ≤1.8 g.
• Pediatric Dose: 5-10 mg/kg per dose based on body weight, strictly adjusted under medical guidance to avoid overdose.

Adverse Reactions and Contraindications

1. Serious Adverse Reactions (Requires Caution)
   • Hematological Toxicity: May cause agranulocytosis (rare but life-threatening), thrombocytopenic purpura, or aplastic anemia, manifested as fever, sore throat, and bleeding tendencies.
   • Allergic Reactions: Skin rashes, urticaria, angioedema; severe cases may lead to anaphylactic shock or laryngeal edema.
   • Local Reactions: Pain, redness, or even induration/necrosis at the injection site.
   • Other: Long-term use may cause renal damage or gastrointestinal bleeding.
2. Contraindicated Populations
   • Individuals allergic to metamizole or pyrazolone-class drugs.
   • Those with a history of granulocytopenia or current granulocytopenia.
   • Pregnant and lactating women (especially in early pregnancy, due to teratogenic risks).
   • Neonates and premature infants (immature liver/kidney function increases toxicity risk).

Precautions

1. Cautious Use in:
   • Patients with hepatic/renal insufficiency, the elderly, or frail individuals.
   • Asthmatics (may trigger bronchospasm).
2. Monitoring During Treatment
   • Avoid long-term use; regularly check blood counts (especially granulocyte counts) during therapy.
   • Discontinue immediately and seek medical help if symptoms like sore throat, fever, or petechiae occur.

Clinical Status and Alternative Drugs

• Restricted Use: Due to severe hematological adverse reaction risks, many countries (e.g., the U.S., some EU nations) have banned or strictly limited analgin's clinical use.
• Alternatives: Clinicians increasingly prefer safer options like paracetamol or nonsteroidal anti-inflammatory drugs (NSAIDs, e.g., ibuprofen) for fever and pain management.

      Company Introduce

1. • 
   • Related Products
     
     
     
     
     
     
     RFQ
     Q: Are you a manufacturer?
     A: Yes, we have established our own factory since 2002, with the latest GMP certification, independent R&D center, and advanced production equipment. The group has been listed as a reputable brand by CCTV. We can strictly control product quality to ensure you can buy high-quality, cost-effective products.
     
     Q: What products can you provide?
     A: We have multiple production lines for powders, injections, premixes, oral liquids, and biological additives, we are leaders in the production of veterinary drugs, animal feed, feed additives, pharmaceutical intermediates, pharmaceutical raw materials. Our diverse range of products includes offerings for pets, poultry, cattle, sheep, pigs, and aquatic species.
     
     Q: Do you test all your goods before delivery?
     A: Yes, we conduct 100% testing before delivery to ensure that each batch of veterinary drugs undergoes strict quality testing, and if you require, we warmly welcome third-party testing with international authorization for our products.
     
     Q: Can we have the sample?
     A: Of course, you can place a sample order first to test the company's quality and service. For some products, we can provide free samples.
     
     Q: What is the MOQ (minimum order quantity)?
     A: We have a significant advantage in MOQ because we offer small MOQ. 100 bottles of injection and 1kg of powder.
     
     Q: Can I use my own design package?
     A: Yes, OEM service is available. We can customize packaging and labels to create a unique brand for dealers. In addition, we can also customize specifications and formulas according to different requirements.
     
     Q: How about delivery time?
     A: We have ample inventory and are ready to ship. Most of our factory orders are normally shipped within 3-5 days upon receiving your payment.
     
     Q: Do you provide after sales service?
     A: We have a clear division of work and offer after-sales service within 8 hours. If there are any quality problems, we will be responsible to the end.
     
     
     
     
2. 
   
   
   Company Introduce