Product Description
Florfenicol solution is a veterinary broad-spectrum antibacterial preparation containing florfenicol as the main ingredient. It inhibits bacterial protein synthesis by binding to the 50S subunit of bacterial ribosomes, effective against Gram-positive/negative bacteria and mycoplasma. Rapidly absorbed and widely distributed, it treats respiratory infections (e.g., swine pleuropneumonia, avian chronic respiratory disease), digestive tract infections (e.g., colibacillosis, fowl cholera), and other bacterial diseases in livestock/poultry/fish (aquatic use follows standards). Administered orally, via IM injection, or in drinking water (e.g., 20-30 mg/kg for swine, 50-100 mg/L for poultry), dosages vary by formulation. Contraindicated in allergic animals; use cautiously in lactating/laying ones. Avoid long-term single use to prevent resistance, and follow withdrawal periods (e.g., 14 days for swine). May cause bone marrow suppression or diarrhea. Avoid mixing with β-lactams/antacids. Store sealed in a cool, dry, dark place. A veterinary prescription drug, it's for animal use only, ensuring compliance with residue standards for food safety.
Introduction
Florfenicol solution is a veterinary antibacterial preparation with florfenicol as the main ingredient. The following is an introduction covering its composition, mechanism of action, pharmacological properties, indications, usage, precautions, etc.:
Main Ingredient
- Active ingredient: Florfenicol, belonging to the amphenicol class of broad-spectrum antibiotics.
Mechanism of Action
- It inhibits bacterial protein synthesis by binding to the 50S subunit of bacterial ribosomes, preventing peptide chain elongation and thus suppressing bacterial proliferation.
Pharmacological Properties
- Broad antibacterial spectrum: Effective against both Gram-positive bacteria (e.g., Staphylococcus aureus, streptococci), Gram-negative bacteria (e.g., E. coli, Salmonella, Pasteurella), and mycoplasma.
- Absorption and distribution: Rapidly absorbed after oral administration or injection, widely distributed in animals, capable of crossing the blood-brain barrier and placental barrier to maintain effective concentrations in the respiratory tract, digestive tract, body fluids, and tissues.
- Drug resistance: No complete cross-resistance with other chloramphenicol-class drugs, but long-term use still requires attention to resistance development.
Indications
- Mainly used for treating bacterial infections in livestock and poultry, such as:
- Respiratory infections: Swine infectious pleuropneumonia, (enzootic pneumonia), swine pasteurellosis; avian chronic respiratory disease, etc.
- Digestive tract infections: Swine colibacillosis, salmonellosis; avian colibacillosis, fowl cholera, etc.
- Other infections: Bacterial enteritis and metritis in cattle and sheep; bacterial septicemia in fish (use according to aquatic medication standards).
Usage and Dosage
- Administration routes: Usually via oral, intramuscular injection, or mixed drinking water, with specific adjustments based on animal species, body weight, and condition.
- Example dosages (based on common veterinary formulations):
- Swine: Intramuscular injection, 20-30 mg/kg body weight, once daily for 3-5 days.
- Poultry: Mixed drinking water, add 50-100 mg per liter of water, used for 3-5 days.
- Note: Different formulations (e.g., injections, oral liquids) have varying concentrations. Strictly follow the product instructions or veterinarian's advice to avoid overdose.
Precautions
- Contraindications and caution:
- Contraindicated in animals allergic to florfenicol.
- Use with caution in lactating animals, laying hens (for some formulations), and animals with renal insufficiency.
- Resistance and withdrawal period:
- Avoid long-term single use to prevent enhanced bacterial resistance.
- Withdrawal period must comply with national regulations (e.g., 14 days for swine intramuscular injection, subject to the drug label).
- Adverse reactions:
- High doses may inhibit bone marrow hematopoiesis, causing leukopenia.
- May lead to gastrointestinal flora imbalance and symptoms like diarrhea.
- Drug incompatibilities:
- Do not use concurrently with β-lactams (e.g., penicillins, cephalosporins) or lincomycin, as antagonism may occur.
- Avoid (co-administration) with antacids (e.g., sodium bicarbonate) to prevent reduced efficacy.
- Personnel protection:
- Operators should avoid skin contact or inhalation of the solution; rinse with water immediately if exposed.
Storage and Packaging
- Storage: Store sealed in a cool, dry place, away from direct sunlight and out of reach of children and animals.
- Packaging: Commonly in plastic or glass bottles, with specifications varying for veterinary injections, oral liquids, etc.
| Storage & Packaging |
- Storage: Store sealed in a cool, dry place away from light, out of reach of children/animals.
- Packaging: Plastic/glass bottles, available in veterinary injections, oral liquids, etc. |
| Regulations & Safety |
Veterinary prescription drug; use under veterinary guidance; strictly prohibited for human use; adhere to national standards for veterinary drug residues to ensure food safety. |
Company Introduce
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RFQ
Q: Are you a manufacturer?
A: Yes, we have established our own factory since 2002, with the latest GMP certification, independent R&D center, and advanced production equipment. The group has been listed as a reputable brand by CCTV. We can strictly control product quality to ensure you can buy high-quality, cost-effective products.
Q: What products can you provide?
A: We have multiple production lines for powders, injections, premixes, oral liquids, and biological additives, we are leaders in the production of veterinary drugs, animal feed, feed additives, pharmaceutical intermediates, pharmaceutical raw materials. Our diverse range of products includes offerings for pets, poultry, cattle, sheep, pigs, and aquatic species.
Q: Do you test all your goods before delivery?
A: Yes, we conduct 100% testing before delivery to ensure that each batch of veterinary drugs undergoes strict quality testing, and if you require, we warmly welcome third-party testing with international authorization for our products.
Q: Can we have the sample?
A: Of course, you can place a sample order first to test the company's quality and service. For some products, we can provide free samples.
Q: What is the MOQ (minimum order quantity)?
A: We have a significant advantage in MOQ because we offer small MOQ. 100 bottles of injection and 1kg of powder.
Q: Can I use my own design package?
A: Yes, OEM service is available. We can customize packaging and labels to create a unique brand for dealers. In addition, we can also customize specifications and formulas according to different requirements.
Q: How about delivery time?
A: We have ample inventory and are ready to ship. Most of our factory orders are normally shipped within 3-5 days upon receiving your payment.
Q: Do you provide after sales service?
A: We have a clear division of work and offer after-sales service within 8 hours. If there are any quality problems, we will be responsible to the end.
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